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"Education is the most powerful weapon which you can use to change the world”
– Nelson Mandela

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critical thinking questions wk 6

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Q 1. Why do you think females are typically the carriers of sex-linked traits, but those traits are not expressed? 2. Cystic fibrosis (CF) is an autosomal recessive disease. Jane and John do not have CF but are worried about having a child who will have it, because John had a brother with the disease. While meeting with a genetic counselor it was determined that John’s parents were not affected with CF, yet his brother had it. What is immediately known about the genotypes of John’s parents? Is the genotype of John immediately known? Under what circumstances could John and Jane have a child with CF?

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1. Sex linked traits are produced by genes found on the sex chromosomes (X and Y). The females are homozygous x, so they have 2 x chromosomes (XX). Males are heterozygous x, so they have 1 x chromosome (XY). Most of the sex-linked traits are X linked because the X chromosome is larger than the Y chromosome and it contains more genes than the Y chromosome. A woman can be a carrier because since they have two X chromosomes. In women, a recessive allele on one X chromosome is often masked in their phenotype by a dominant normal allele on the other. This explains why women are frequently carriers of X-linked traits but more rarely have them expressed in their own phenotypes